Prof. David Arnot completed his PhD at the University of Cambridge. He has worked in Boston and New York in the United States as a postdoctoral fellow and assistant professor. He began working for The University of Edinburgh in 1989 working as a Wellcome Trust Senior Fellow for the Department of Genetics & Institute of Cell & Population Biology, University of Edinburgh. His most recent position was Professor of Molecular Parasitology with the Institute of Immunology & Infection Research, University of Edinburgh. As a malariologist, he has carried out several malaria field projects, working in Tanzania and Ghana and visiting Burkino Fasso, Egypt, Gabon, Ethiopia, Kenya, Malawi, and Mozambique. Since 2010 he has served as Director for Internationalisation for the School of Biological Sciences and interacts frequently with the University’s partners in China, India, and Singapore.
Dr Mikael Bjorklund received his PhD in Biochemistry in 2004 from the University of Helsinki, Finland. He did his post-doctoral training also in Helsinki, implementing genome-scale approaches to his main research on cell growth. In 2009, Mikael started as a principal investigator in Scotland and obtained a prestigious Wellcome Trust Career Development fellowship to support his research. Mikael's main scientific interest is how metabolism and cell size impact cellular fitness and functions and how these are linked to initiation and disease progression in cancers and other metabolic diseases.
Dr Wei completed his PhD in Molecular Genetics at University of Texas Graduate School of Biomedical Sciences in 2002. He has worked as the postdoctoral fellow for the University of California and most recently as Tenure-track Associate Professor at Tsinghua University, China. His previous research had focused on the study of stem cells and cancer, as well as the role of the PTEN tumor suppressor in hematopoietic stem cells and leukemia.
Professor Ahmed Hashash completed his PhD from Manchester University, UK. He is a fellow of the California Institute of Regenerative Medicine (CIRM) and New York University Medical School (MSSM), USA. Prof. Ahmed Hashash worked as a senior biomedical research scientist at Mount Sinai School of Medicine of New York University and Childrens Hospital Los Angeles. He was Assistant Professor and Principal Investigator of Stem Cell & Regenerative Medicine at Keck School of Medicine and Ostrow School of Dentistry of The University of Southern California, USA. In 2016, Prof. Hashash has joined The University of Edinburgh, Edinburgh Medical School-Zhejiang International Campus, (ZJU) as Tenure-Track Associate Professor and Senior Principal Investigator of Biomedicine, Stem Cell & Regenerative Medicine. He is also adjunct Professor at the School of Basic Medical Science and School of Medicine, Zhejiang University. Prof. Hashash has several breakthrough discoveries in genes/enzymes that control stem cell behavior and regenerative medicine.
Dr Sebastian Leptihn is an Associate Professor at the Zhejiang University - University of Edinburgh Institute. He has over ten years experience in academic teaching and research in Germany, Singapore and Oxford, after his PhD at the Technical University of Munich, Germany. His research expertise lies at the interface between biology and chemistry to investigate functional and structural aspects of proteins and protein complexes, with the focus on membrane proteins. As the gatekeepers of cells, membrane proteins represent the most important drug targets. To understand fundamental principles of protein insertion, folding and assembly as well as protein function, the Leptihn group uses classical in vitro biochemical and biophysical methods together with state-of-the-art single molecule techniques.
Dr. Xin Xie is currently an Associate Professor at Zhejiang - Edinburgh Institute (Zhejiang) and an Adjunct Assistant Professor at Baylor College of Medicine (Texas). After receiving his PhD in Genetics from Texas A&M University, Dr. Xie joined Baylor College of Medicine as a Postdoctoral Fellow, later he became an instructor and subsequently, an Assistant Professor. During his postdoctoral study, Dr. Xie has investigated the molecular functions of nuclear receptor COUP-TFII in adult stem cell and relevant diseases. Currently, his research interest focuses on the understanding of how signaling network within tissue stem cells (intestinal, muscle and mesenchymal stem cell) regulates their fundamental properties in both physiological and pathological conditions and translates that knowledge into novel therapeutic approaches to improve the outcome of patients suffering stem cell-related disorders.
Dr. Kuan Yoow Chan is currently a Postdoctoral Fellow at the Cancer Research UK Manchester Institute, University of Manchester. He obtained his degree in Medical Genetics from University of Wales, Swansea. During his PhD training at the University of Hull, he worked on identifying drug targets against the human pathogen, African Trypanosomes. He is currently studying the role of the centrosome in regulating the eukaryotic cell cycle. He is ongoing interest is to understand how centrosomal abnormalities contribute to the deregulation of the cell cycle in human cancers.
Dr Chew completed his bachelor’s degree at the National University of Singapore (NUS), before going onto complete his PhD in Cell and Molecular Biology at Temasek Life Sciences Laboratory (TLL), in Singapore in 2009. He has previously held post-doctoral research fellow positions with Institute of Medical Biology (A*STAR, Singapore) and Centre for Mechanochemical Cell Biology (Warwick University, UK). His current research focuses on the molecular mechanisms of cell division, particularly on the mechanical responses of cell division to the extracellular environments. He is also interested in studying consequences of cytokinesis failures during tissue growth.
Dr Wenwen Huang completed her PhD in Tufts University, she worked as a guest lecturer in the department of biomedical engineering at Tufts University from May 2015 to July 2018. Her research interests include polymer physics, biomedical engineering and materials science.
Dr Zhi Hong worked as as a postdoc at the Institute for Cancer Research, Oslo University Hospital. She completed her bachelor’s degree at the College of Agriculture and Biotechnology, China Agricultural University, and went onto complete her PhD in 2011 from the Institute of Genetics & Developmental Biology, Chinese Academy of Sciences. She has worked as a Research Associate for Chinese Academy of Medical Sciences. Her research focuses on studying the molecular mechanism regulating lysosomal bidirectional transport and investigating the role of lysosomal positioning in invadopodia formation and cancer invasion.
Dr Wanlu Liu completed her PhD degree at University of California, Los Angeles. Then she worked as postdoctoral research associate in University of California, Los Angeles, Department of Molecular, Cell and Developmental Biology, co-mentored by Dr. Steven E. Jacobsen and Dr. Amander T. Clark. Her research focuses on studying epigenetics mechanisms in gene regulation and developing tools for epigenome targeting.
Dr Chaochen Wang completed his PhD degree in Shanghai institute of biochemical cells, Chinese academy of sciences. From 2009 to 2018, he was worked in National Institute of Health(U.S.) as a visiting scholar, researcher and full-time scientist. His research interests are epigenetics, gene editing and stem cells.
Dr. Di Chen completed his PhD degree in Chinese Academy of Sciences. Then he continued as a postdoctoral researcher at University of California, Los Angeles (UCLA), focusing on the differentiation of human embryonic stem cells. His lab focuses on the regulatory mechanisms of the differentiation potentials of human embryonic stem cells and/or induced pluripotent stem cells, especially the function of transcription factors, epigenetic regulators and RNA-binding proteins.
Dr. Qianting Zhang completed her bachelor’s degree and PhD degree at Zhejiang University, China. She worked as a postdoc at the Department of Chemistry and Molecular Biology, University of Gothenburg. Her research focuses on dissecting the molecular mechanisms of mammalian gametogenesis and tumorigenesis utilizing mammalian cell lines, gene-modified mouse models and human samples. We investigate: 1) the function and association of key proteins in meiotic synapsis and homologous recombination (HR) and 2) the role of HR-related proteins in genomic instability and tumorigenesis.
Dr Mike Shipston graduated with a 1st class Honours degree in Physiology from the University of St Andrews before completing his PhD at the MRC Brain Metabolism Unit. Following a Wellcome Trust Advanced Training Fellowship hosted in Edinburgh with a period at NIEHS, USA he was recruited to a lectureship in Physiology at the University of Edinburgh in 1997 where he established the Membrane Biology Group. In 2003 he was appointed to the Chair of Physiology and established the Centre for Integrative Physiology. In 2015 he was appointed as Dean of Biomedical Sciences in the new Edinburgh Medical School. His research is particularly focused on post-transcriptional and post-translational mechanisms, such as alternative pre mRNA splicing and protein S-acylation, that control ion channel physiology and how dysregulation may lead to major stress and endocrine related disorders.
Dr John Menzies is a lecturer at ZJE and the Centre for Discovery Brain Research at the University of Edinburgh. John is also the Programme Director for the undergraduate programmes at ZJE. Research in his laboratory focuses on the brain and its crucial role in eating behavior. Unconscious neural systems constantly monitor the body’s energy status and alert us to the availability of particularly energy-dense foods. Because of this, our body weight and food choices are under far less conscious control that we might think. John is interested in the neural correlates of appetite control and food reward, with a view to better understanding energy balance and so-called “food addiction”.
Dr Joanne Murray is an Academic Track Senior Lecturer (Zhejiang) and a Principal Investigator in the Centre for Discovery Brain Science, School of Biomedical Sciences. Joanne is a reproductive biologist with a particular interest in how nutrition can affect the reproductive axis. Three areas of current research are: 1. determining the role of hypothalamic melanin concentrating hormone expression in lactation; 2. characterizing the distribution of and interaction between the melanocortin receptors in the male and female reproductive axes; and 3. studying the role of oxygen in the growth and development of the ovarian follicle.
Dr Michael Daw is a lecturer based in the Centre for Discovery Brain Sciences. Work in the Daw lab studies the development of the electrical properties of neurons and synapses during early life. He has particular expertise in synaptic plasticity and inhibitory interneurons, defects in both of which are implicated in a number developmental disorders. Michael has most recently studied development in genetic models of intellectual disability and epilepsy.
Dr Melanie Stefan is a computational neurobiologist at the Centre for Discovery Brain Sciences at the University of Edinburgh. Her research group revolves around using computers to understand learning and memory across different scales: On a small scale, they simulate how molecules inside the brain work together to strengthen connections between neurons. On the large scale, they want to use data from digital educational tools to understand how students learn. Melanie’s background is in Mathematics and Biology, which she studied in her native Austria. She completed her PhD at the European Bioinformatics Institute in Cambridge (UK), and then went on to do post-doctoral work in Japan and the US. She joined the University of Edinburgh in 2015.
Dr Sander van den Driesche is a tenure-track lecturer at the Zhejiang University - University of Edinburgh Institute and at the University of Edinburgh. Sander obtained his PhD degree at the Hubrecht Institute in the Netherlands, before moving to Edinburgh in 2006, where he joined the MRC Human Reproductive Sciences Unit as a post-doctoral researcher. In 2011 he became senior post-doc at the MRC Centre for Reproductive Health in Edinburgh. Since September 2016 he works for the ZJU/UoE Institute. His research focuses on the fetal origin of male reproductive health disorders and the regulation of the male programming window.
Dr Richard Sloan is a tenure track lecturer at the Zhejiang University - University of Edinburgh Institute and at the University of Edinburgh. Richard obtained his PhD degree from University College London (UCL) in 2007 and then undertook postdoctoral research at the McGill University AIDS Centre in Montreal. He started his own lab at Barts and The London School of Medicine in 2013, before moving up to Edinburgh University to continue his research in the Division of Infection and Pathway Medicine. His research is in the field of intracellular innate immunity and seeks to understand how retroviruses such as HIV can be controlled by innate immune factors. More recently, he has also become interested in how endogenous retroelements in the human genome, such as LINE-1, may be similarly controlled by innate immune factors as occurs with infectious retroviruses like HIV. Collectively, this research may pave the way for new forms of antiviral therapy, provide molecular understanding of immunity and host cell biology, as well as explain patterns of patient disease susceptibility or retroviral zoonosis.
Dr Gracjan Michlewski is a Senior Lecturer (Zhejiang) in Biomedical Sciences at The University of Edinburgh. He obtained his PhD and Habilitation from the Institute of Bioorganic Chemistry, Polish Academy of Sciences in Poznan, Poland. Gracjan has been a postdoctoral fellow in the Human Genetics Unit, Medical Research Council in Edinburgh. In 2011, he established his laboratory at The Wellcome Trust Centre for Cell Biology, the University of Edinburgh with Medical Research Council Career Development Award. Gracjan's main research interests are associated with regulation of gene expression, RNA processing and innate immune response to RNA viruses.
Dr Paula Brunton is currently a Senior Lecturer based at the Centre for Discovery Brain Sciences, University of Edinburgh, UK. She received her bachelor’s degree in Physiology in 1998 and her PhD in Neuroendocrinology in 2002, both from the University of Edinburgh. Next, she completed post-doctoral training at the Universities of Newcastle and Edinburgh, UK. She joined the Roslin Institute as a Career Track Fellow in 2010 and was promoted to Senior Research Fellow and Group Leader in 2015. Her expertise lies in the area of stress neurobiology, neuroendocrinology and behaviour. Her key research themes are focused on understanding the impact of maternal stress exposure during pregnancy on the mother, the pregnancy, her offspring and on subsequent generations, with a particular emphasis on unearthing the underlying central mechanisms involved and how the effects can be prevented or reversed.
Dr Laura O'Hara is currently researching the mechanisms by which steroid hormones such as androgens and estrogens act in the hypothalamus and pituitary to control male reproduction and testosterone production. She is also interested in improving the way that biological pathways are depicted as diagrams and have been involved in developing the modified Edinburgh Pathway Notation (mEPN) for use as a dynamic modeling system.
A graduate of the University of Milan, Italy, Dr Nicola Romanò got his PhD at the University of Otago, Dunedin, NZ. His PhD focussed on the rapid effects of estrogen on GnRH neurons, that control fertility. After completing his PhD, he spent six years at the Institute of Functional Genomics in Montpellier, focussing on the systems that control prolactin secretion. He is generally interested in how hormonal systems adapt to changes in environment, and how that relates to hormonal rhythms. In particular, his research investigates the rhythms of the hormones produced by the pituitary gland, their generation at the cellular and molecular level, and how they affect body physiology. He has a particular interest in the stress and the reproductive axes, and their physiological interactions.
Dr Gedi Luksys is a Lecturer at the University of Edinburgh’s Centre for Discovery Brain Sciences (previously at the Centre for Cognitive and Neural Systems) and at ZJU-UoE Institute. His research explores several directions of computational cognitive neuroscience, such as modeling animal and human behaviour in various learning, memory and decision-making setups, studying the role of schemas, and employing multi-voxel pattern analysis. He also investigates computational roles of stress and other modulators, how they interact with individual traits to control behaviour and cognition, and how they can be used to improve cognitive performance and alleviate adverse effects of mental disorders.
Dr. Matthew Brook is a tenure track lecturer at the Zhejiang University - University of Edinburgh Institute. Dr. Matthew Brook obtained his PhD degree from Imperial College London at 2006 and then started to work at University of Edinburgh. Now he is a Senior Research Associate at BHF Centre for Cardiovascular Sciences, University of Edinburgh.
Dr Rob Young is a tenure track lecturer at the Zhejiang University – University of Edinburgh Institute and at Edinburgh University’s Usher Institute. He obtained his DPhil from the University of Oxford in 2012 and carried out postdoctoral research at the MRC Human Genetics Unit, MRC IGMM at the University of Edinburgh. His research integrates genomics and population-wide datasets to understand how variation outside gene borders within the noncoding genome drives complex phenotypes and disease. He has a particular focus on promoters, which are noncoding regulatory loci responsible for regulating gene expression initiation and which are significantly enriched for phenotype-associated variants. He has also identified that promoters experience pervasive evolutionary volatility and is interested in what this rewiring can tell us about how variation across individuals, populations and species arises and is regulated.
Professor of Zhejiang University school of medical, doctoral supervisor. Dr Junfeng Ji has completed postdoctoral work in McMaster Stem Cell and Cancer Research Institute and Ontario Institute for Cancer Research. In 2012, he joined Zhejiang university.The main research direction is Stem cell fate regulation mechanism, Cellular senescence and aging-associated diseases.
Dr Yuehai Ke completed his PhD at the Fudan University Institute of Genetics. His basic research focuses on pulmonary signal transduction, respiratory molecular medicinemolecular cell biology, interstitial pneumonia, and pulmonary vascular disease.
Dr Xiang-Yao LI received his Ph.D degree in Physiology in East China Normal University in 2007. Thereafter, he worked as a post-doctoral Fellow in the physiology department of University of Toronto, supervised by Prof. Min Zhuo. He returned to Xi’an Jiaotong University as a faculty in 2012. Later on he moved to Zhejiang University in 2014, His research mainly focuses on the energy metabolism and information coding change involved in the neuropathic or inflammatory pain. He established a systematic pain study platform and a drug evaluation platform for the effects on Chronic pain.
After obtaining a BS degree in Chemistry in Peking University in China in 2001, Dr. Pan was recruited in a PhD program in Biochemistry in the University of Pennsylvania in the US and obtained his PhD in 2007. Dr. Pan was recruited by Zhejiang University School of Medicine in October 2015. He is now a principle investigator in the Department of Medical Microbiology and Parasitology. He has published research papers in Cell Host Microbe，PNAS，Mol Cell，Nat Struct Mol Biol，J Infect Dis，J Virol, J Biol Chem, etc as the first author, and many more as co-authors. Now his research is focused on molecular mechansms of herpes simplex virus pathogenesis, latency and immune evasion, and is aimed at developing new antiviral therapeutics.
Dr Stijn van der Veen is a professor in Microbiology and Assistant Dean at the Zhejiang University School of Basic Medical Sciences. He received his PhD at Wageningen University, The Netherlands, where he worked on stress survival of the bacterial pathogen Listeria monocytogenes. He subsequently became postdoctoral researcher and lecturer at Wageningen University and investigated the mechanisms that L. monocytogenes employs to form biofilms and generate diversity. Afterwards, he became research associate at the Sir William Dunn School of Pathology at the University of Oxford, UK, where he studied host-microbe interactions and vaccine development against Neisseria meningitidis. He has published over 30 papers in international high-impact peer-reviewed journals such as PLoS Pathogens, Journal of Antimicrobial Chemotherapy, Infection and Immunity, International Journal of Medical Microbiology and Proceedings of the National Academy of Sciences of the USA. His current research is focused on the mechanisms to that Neisseria gonorrhoeae and N.meningitis employ to colonize the human host and cause disease and translate this knowledge to the development of vaccines and targets for intervention.
Prof. Lie Wang got his in Biochemistry and Molecular Biology from Shanghai Institutes of Biochemistry and Cell Biology (SIBCB), Chinese Academy of Sciences, Shanghai, China in 2004 and then undertook postdoctoral research in Remy Bosselut’s laboratory, Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD (Oct 2004-May 2010). He started his own lab in 2010 to study the development of T-lymphocytes in the thymus, which, as one of a few developmental processes that persist throughout life, is a privileged model to study the basic mechanisms of cell differentiation. His work has identified a gene encoding a transcription factor ThPOK (cKrox/Zbtb7b) of the “zinc-finger” family that promotes CD4 T cell differentiation in the thymus. He also demonstrated that directly controls the expression of key genes important for thymocyte survival and for T-cell receptor signaling, through maintaining the appropriate H3K4me3 on their promoters. Key Research: Nature immunology, Immunity, Nature communication.
Dr Xiaohang Yang completed his PhD programme in biochemistry from the Dartmouth College before going onto hold positions at world-renowned institutes including MIT, National University of Singapore and IMBC. His research interests are in neurodevelopment.
Dr Yiting Zhouceived received his PhD from the National University of Singapore (Prof Low Boon Chuan Lab) in 2005 and received post-doctoral training and promotion from the Prof Low Boon Chuan Lab and the Prof Emanuel Hanski lab from 2005 to 2011. Since 2012, his work has focused on the study of motor system diseases and stem cell differentiation mechanisms, including muscle differentiation, mesodermal stem cell differentiation to tendon, and osteoarthritis-related molecular mechanisms. Current research findings include: the regulatory mechanism of the synergistic interaction between Rab and molecular motor proteins on myoblast differentiation, and the abnormally high expression of Rac1 activity in osteoarthritis.
Dr Zhou is a professor at Zhejiang University School of Medicine and an adjunct professor at the Zhejiang University - University of Edinburgh Institute. Zhou received his B.S. in Biology from Hangzhou University, his M.S. in Neurobiology from Shanghai Brain Research Institute, Chinese Academy of Sciences, and his PhD in Neuroscience from Tufts University. After postdoctoral work at Boston University and Harvard Medical School, Zhou joined the faculty of Neurobiology at Zhejiang University in 2011, where he is a principal investigator in the Institute of Neuroscience and the Key Laboratory of Medical Neurobiology of the Ministry of Health of China. Zhou's research focuses on investigating how inflammatory signaling events interfere with brain circuit formation, causing severe neurological and metabolic conditions. Studying neuroinflammation during development facilitates our understanding of the fundamental mechanisms underlying neural network development, synaptic plasticity, and circuit dynamics, and sheds light on neurodevelopmental and metabolic diseases such as childhood epilepsy, autism, and obesity.