Here, we present the human Antigen Receptor database (huARdb), a large-scale human single-cell immune profiling database that contains 444 794 high-confidence T or B cells (hcT/B cells) with full-length TCR/BCR sequence and transcriptomes from 215 datasets. Our database contains single-cell immune profiling data from various tissue types and disease settings. We also developed a multi-functional and user-friendly web interface that provides interactive visualization modules for biologists to analyze the transcriptome and TCR/BCR features at the single-cell level. huARdb is freely available at https://huarc.net/v2/ with functions for data querying, browsing, downloading, and depositing.